Trichoblastomas derived from the facial skin with tactile hair in aged house musk shrews (Suncus murinus)

    December 2022 in “ Laboratory Animal Research
    Tohru Kimura
    TLDR Trichoblastomas in aged house musk shrews show unique features and may involve serum amyloid A in inflammation.
    This case report describes the first known instances of trichoblastomas, benign hair follicle tumors, in the facial skin with tactile hair of aged house musk shrews (Suncus murinus). Two cases were identified, with affected shrews showing symptoms like weight loss and anemia. Histopathological analysis revealed unique features such as basaloid islands and microcysts, differing from those in humans and other animals. The study highlights that these tumors reflect aspects of embryological development in tactile hair follicles and suggests that serum amyloid A plays a role in the inflammatory response, consistent across mammals.
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