Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: Potential role of endogenous neurosteroids?
August 2005
in “Alcohol”
TLDR Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.
This study investigated the effects of finasteride, a drug used to treat hair loss, on ethanol intake patterns in male mice. The results showed that acute treatment with finasteride reduced ethanol intake, while chronic treatment and withdrawal had varying effects. The study suggests that endogenous neurosteroids may play a role in the potential effects of finasteride on ethanol intake. The study highlights the potential for drugs used for hair loss to have unintended effects on alcohol consumption.
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research Effects of Finasteride on Chronic and Acute Ethanol Withdrawal Severity in the WSP and WSR Selected Lines
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research GABRA2 Alleles Moderate the Subjective Effects of Alcohol, Which are Attenuated by Finasteride
GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
research Interaction of chronic ethanol exposure and finasteride: sex and strain differences
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