Successful Treatment of Ulcerated Infantile Hemangioma Associated with PELVIS Syndrome Using Oral Propranolol

The document reports a case of a male infant with PELVIS syndrome, which is characterized by segmental hemangioma with genital and systemic abnormalities. The infant was initially misdiagnosed with diaper rash but was later found to have atypical genital features and spinal cord and vesicorenal abnormalities. Treatment with oral propranolol led to a decrease in the size and ulceration of the hemangioma. Additionally, multistep surgical repair was performed for the external genital malformations and tethered spinal cord. The case emphasizes the importance of accurate diagnosis of suspicious lesions, as they can be indicative of systemic anomalies with potential long-term complications. The successful use of oral propranolol for treating ulcerated segmental hemangiomas in PELVIS syndrome was confirmed. No commercial support was identified for this study.