Treatment of Female Androgenic Alopecia with Cimetidine

    September 1987 in “ International Journal of Dermatology
    Alan Edwin Creenwald
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    TLDR Cimetidine is not a first-choice treatment for female hair loss, and there's no consistently successful treatment for this condition in men or normal hormone level women.
    The document discusses the treatment of alopecia areata in a 2½-year-old girl using a combination of intralesional injections of triamcinolone acetonide, betamethasone dipropionate ointment, and topical 3% minoxidil. Over a period of approximately 3½ months, the patient experienced hair regrowth in the affected areas as well as unintended hair growth on the forehead, nape of the neck, and sacroiliac area, resulting in a "tail-like effect." The document also references a correspondence regarding the treatment of female androgenetic alopecia with cimetidine, noting that cimetidine is not considered a first-line drug for this condition. The author, Dr. Homayoun Aram, acknowledges that there are no consistently successful treatments for androgenetic alopecia in men or endocrinologically normal women and expresses regret for not referencing Dr. Wilma Bergfeld's work on spironolactone for adrenal androgenic female-pattern alopecia. Dr. Aram also confirms his move to California and his disconnection from the Center for Skin Diseases in Jerusalem. The number of people mentioned in the treatments discussed varies, with one case of the young girl and anecdotal references to other patients, including 27-year-old female twins and a male patient, without specific numbers for the latter cases.
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