The stumptailed macaque as a model for baldness: effects of minoxidil

    Hideo Uno
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    TLDR Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.
    The study investigated the effects of minoxidil on baldness in stumptailed macaques, which is biologically similar to male pattern baldness in humans. The researchers found that topical application of minoxidil induced regrowth of terminal hairs in bald scalps of macaques, with greater results in the early stages of baldness in adolescent and young adults. Minoxidil also prevented the development of baldness when applied on non-bald scalps of peri-adolescent animals. The study concluded that the stumptailed macaque is a useful animal model for the study of human male pattern baldness, and minoxidil has no influence on epidermal keratinocytes, sebaceous glands, and other dermal components.
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