The Effect of Anti-Androgens on the Response of Rat Preputial Glands to Testosterone
September 1964
in “
The journal of investigative dermatology/Journal of investigative dermatology
”
TLDR New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.
The document discusses the discovery of new compounds with anti-androgenic effects that counteract the influence of testosterone in experimental animals without significant estrogenic effects. These compounds are considered potentially useful for treating diseases thought to be exacerbated by androgens, including prostate cancer, acne vulgaris, hirsutism, and male pattern baldness. The research is focused on the response of rat preputial glands to testosterone and the impact of anti-androgens on this response.
