Approved Systemic Drugs Needed for Dermatosis Like Alopecia Areata, Hidradenitis, and Vitiligo: A SPIN-FRT Evaluation

The document highlights the need for improved systemic treatments for chronic cutaneous immune-mediated inflammatory diseases (IMIDs) such as alopecia areata (AA), hidradenitis suppurativa (HS), and vitiligo (VT). While significant progress has been made in treating psoriasis (PsO) and atopic dermatitis (AD), with 19 and 7 approved systemic treatments respectively, there are only 3 approved treatments for both HS and AA, and none for VT. The SPIN (Skin Inflammation and Psoriasis International Network) emphasizes the importance of addressing these unmet needs by developing more evidence-based guidelines and innovative therapies. The document also stresses the necessity of incorporating patient perspectives into clinical research and the importance of real-world data to inform treatment guidelines.