27 citations
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December 2015 in “Clinical and Experimental Dermatology” Diphencyprone helped most patients with alopecia areata regrow some hair.
421 citations
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April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
35 citations
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March 2010 in “Journal of Dermatological Science” The study evaluated the use of ebastine, a second-generation anti-histamine, as a supportive treatment for alopecia areata (AA). Ebastine, known for its role in treating allergic conditions, was found to promote hair regrowth in patients with intractable AA. Two case studies were highlighted: a 25-year-old female with atopic dermatitis and a 40-year-old female with progressive AA, both of whom showed significant improvement after ebastine treatment. The drug's ability to suppress Th2-type proinflammatory cytokines and inhibit T cell migration was suggested as a mechanism for its effectiveness, given the T cell-mediated inflammatory destruction observed in AA.
244 citations
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January 2010 in “Journal of the American Academy of Dermatology” The document says current treatments for alopecia areata do not cure or prevent it, and it's hard to judge their effectiveness due to spontaneous remission and lack of studies.
71 citations
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March 2009 in “Seminars in cutaneous medicine and surgery” Alopecia areata can cause unpredictable hair loss, and treatments like corticosteroids and minoxidil may help but have varying side effects.