Sodium Valproate-Induced Kinky Hair

    February 2001 in “ PubMed ”
    S Caneppele, J. Mazereeuw‐Hautier, J L Bonafé
    TLDR A medication called sodium valproate likely caused a girl's hair to become kinky and dry.
    In 2001, a case study reported a 6-year-old girl who developed acquired progressive kinking hair syndrome, a rare pilar dysplasia, likely induced by sodium valproate. This was the first case of its kind. The girl's hair became kinky, lusterless, dry, and exhibited an aspect of pseudo-pili torti under light microscopy. The report suggested that sodium valproate should be considered as a potential cause of kinky hair syndrome, as five other cases of valproate-induced pilar dysplasia had been reported, albeit without clinical descriptions.
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