A Systemic Lupus Erythematosus Patient With Multiple Aseptic Bone Necroses, Thrombosis of Superior Mesenteric Artery and Anti-Phospholipid Antibody

    October 1992 in “ PubMed ”
    J Masuyama, T. Umino, Masaru Murata, Taku Yoshio, A Takeda, M Kuriyama, Morito Sumiya, Satoru S. Kano
    TLDR Anti-phospholipid antibodies in SLE can cause thrombosis and bone necrosis.
    A 38-year-old woman with systemic lupus erythematosus (SLE) experienced multiple aseptic bone necroses and thrombosis of several arteries, including a complete obstruction of the superior mesenteric artery (SMA). Despite conservative treatment, surgical intervention was required to resect parts of the small intestine and right colon. The presence of anti-cardiolipin and lupus anticoagulant antibodies suggested that the thrombosis was related to anti-phospholipid antibodies. The case highlighted the association between anti-phospholipid antibodies and both thrombosis and bone necrosis in SLE patients.
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