TLDR Certain fungi may contribute to hair loss in cynomolgus macaques.
This study investigated the association between alopecia and skin mycobiota in cynomolgus macaques by analyzing skin swab samples from 47 healthy and 50 alopecic macaques using Oxford Nanopore Technologies. The results revealed significant differences in alpha and beta diversities between alopecic and healthy macaques across five body areas. Specific fungi, such as *Wallemia sebi*, *Candida albicans*, *Rhodotorula mucilaginosa*, *Exophiala dermatitidis*, and *Candida parapsilosis*, were associated with alopecia in various regions. The study suggests that these microorganisms may contribute to alopecia development, offering insights for future biomedical research and therapeutic strategies in primate facilities.
9 citations
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April 2023 in “Frontiers in immunology” New technologies help us better understand how skin microbes affect skin diseases.
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April 2017 in “Journal of Investigative Dermatology” The gut microbiome affects the development of alopecia areata.
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June 2016 in “Journal of Medical Primatology” Captive management practices affect hair loss and stress in rhesus monkeys, with differences between facilities.
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February 2011 in “Current Zoology” About 20% of Japanese macaques had head alopecia, and stress and environment might cause hair loss.
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May 2009 in “Veterinary Dermatology” The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.
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January 2024 in “Microorganisms” Dupilumab improves skin microbiome balance in atopic dermatitis patients.
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April 2022 in “Microorganisms” People with severe hair loss (Alopecia Areata) have different scalp bacteria than healthy people, which might help predict the condition's progress.
October 2020 in “Veterinary Dermatology” New treatments and diagnostic methods for various animal skin conditions showed promising results.
3 citations
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October 2022 in “Frontiers in Surgery” Proteomics combined with other technologies can lead to a better understanding of skin diseases.
5 citations
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May 2023 in “Frontiers in immunology” Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
