The Skin Manifestations in End-Stage Renal Disease Patients in Jordan: Single-Center Experience

    January 2025 in “ BMC Nephrology ”
    Mohammad Hassan Al-thnaibat, Heba M. Urabi, Hadeel S. Alkofahi, Ola Mohannad Alshriedeh, Raneem Alshraideh, Hanan Esmadi, Ahmed Al-Sheyyab, Bakri Roumi Jamal, Hanan Hasan
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    Studysummary This study reported that 83.1% of patients with end-stage renal disease on hemodialysis experienced skin conditions, with xerosis affecting 63.6%, pruritis 36.4%, and notable occurrences of nail and oral anomalies, indicating a need for targeted dermatological management to improve patients' quality of life. Our plain-language summary of this paper — not a Tressless recommendation.
    The study conducted at Prince Hamza Hospital in Jordan evaluated skin manifestations in 77 end-stage renal disease (ESRD) patients undergoing hemodialysis. It found that 83.1% of participants experienced skin conditions, with generalized xerosis (63.6%) and pruritus (36.4%) being the most common. Additionally, 22.1% experienced diffuse scalp hair loss. The study emphasizes the importance of early recognition and management of these dermatological issues to reduce the physical and psychological burden on ESRD patients, and suggests further research into underlying mechanisms and treatments. Key risk factors include prolonged diabetes, hypocalcemia, and reduced serum iron.
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