Skin and Hair Regeneration After Calciphylaxis

The study on skin and hair regeneration after calciphylaxis in rats revealed that while the calcified carapace formed during calciphylaxis did not include the complete skin, enough connective tissue and epithelium remained to allow for some regeneration. However, this regeneration was incomplete and resembled scar tissue, lacking restored elastic fibers and showing a significant reduction in hair numbers. It was unclear whether the regrowth of hair was due to surviving hair roots or new hair formation. Additionally, there was a notable increase in calcium in growing hairs and a lack of alcian blue stainable substances in mast cell granules post-calciphylaxis.