Faculty Opinions Recommendation of Sex Hormone-Binding Globulin and Risk of Hyperglycemia in Patients with Androgenetic Alopecia
TLDR People with early onset baldness (AGA) have higher blood sugar levels and lower sex hormone-binding globulin (SHBG) levels, suggesting SHBG could predict high blood sugar in these individuals.
The study found a strong association between early onset androgenetic alopecia (AGA), hyperglycemia, and low levels of sex hormone-binding globulin (SHBG). AGA has been linked to an increased risk of cardiovascular events, but its association with diabetes mellitus type 2 and hyperglycemia has been unclear. In this case-control study, AGA patients had higher fasting glucose levels and lower levels of SHBG compared to controls. This suggests that SHBG may be a marker for predicting the development of hyperglycemia in AGA patients. However, larger prospective trials are needed to confirm these findings and determine the cause and effect mechanism.
