Self-assembling peptide hydrogel scaffolds support stem cell-based hair follicle regeneration
October 2016
in “Nanomedicine: Nanotechnology, Biology and Medicine”
TLDR Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
This study from 2016 investigated the use of self-assembling peptide hydrogel scaffolds to support stem cell-based hair follicle regeneration. The researchers found that the hydrogels were effective in promoting the growth and differentiation of skin-derived precursor cells (SKPs) into hair follicles, with the RADA16 and PRG mixture being particularly effective. The study suggests that self-assembling peptide hydrogel scaffolds have potential for use in hair follicle regeneration and tissue engineering.
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Cited in this study
research Emerging interactions between skin stem cells and their niches
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research Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach
The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells
SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
research Hair follicle neogenesis induced by cultured human scalp dermal papilla cells
Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.
research Scratching the surface of skin development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.