Screening for Anti-inflammatory Activities in Extracts from Korean Herb Medicines

    March 2014 in “ Journal of the Society of Cosmetic Scientists of Korea ”
    Sang Mi An, Hyoung Gun Kim, Eun Jung Choi, Hyoung Hoon Hwang, Eunseok Lee, Ji Hwoon Baek, Yong Chool Boo, Jae Sook Koh
    TLDR Some Korean herb extracts can reduce inflammation and are safe for skin use.
    The study investigated the anti-inflammatory activities of 51 Korean herb medicine extracts using RAW264.7 macrophage cells. Ten ethanol extracts, including those from Biotae Orientalis Folium and Cyperi Rhizoma, were found to reduce cytotoxicity and inhibit the production of inflammatory mediators like Nitric oxide (NO), interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α in lipopolysaccharide (LPS)-induced cells. These extracts also did not cause skin irritation in human patch tests, suggesting their potential as cosmetic agents to prevent skin irritation.
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