Review of Cardiovascular Findings in Humans Treated with Minoxidil

    January 1989 in “Toxicologic Pathology
    Joseph T. Sobota
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    TLDR Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.
    Minoxidil, a drug used for hypertension and hair loss, has been found to cause cardiac lesions in canines, but there is no evidence of cardiovascular issues in humans. However, some studies have reported changes in the heart, and caution should be taken when using minoxidil in patients with pre-existing cardiovascular conditions. While some reviews suggest that minoxidil is safe for cardiovascular health in humans, others suggest that it can cause significant cardiac pathology, including pericarditis and myocardial infarction. Patients taking minoxidil should be monitored for potential heart-related issues, especially those with pre-existing heart conditions. Further research is necessary to fully understand the drug's impact on the heart.
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