A Review on Palitya and Dhatryadi Rasayana

The document reviews the use of Dhatryadi Rasayana, an Ayurvedic polyherbal formulation, in treating premature hair greying (Palitya). It attributes premature greying to the vitiation of Pitta dosha and factors like oxidative stress and nutritional deficiencies. The formulation includes Dhatri (Emblica officinalis Gaertn.), Bhringraj (Eclipta alba Hassk.), and Tila (Sesamum indicum Linn.), which are believed to promote hair growth and pigmentation. Eclipta alba is highlighted for its active compounds that stimulate hair follicle keratinocytes and reduce the time for hair growth initiation, while Sesamum indicum is noted for its 5α-reductase inhibition, which is important for preventing hair loss and increasing hair pigmentation. The document suggests that herbal medicines like Dhatryadi Rasayana, with their antioxidant properties and nutritional benefits, could be safer and more effective than synthetic drugs for preventing premature greying. However, it acknowledges the lack of empirical data to support the efficacy of this treatment.