Relationship Between Serum Testosterone Levels and Kidney Stones Prevalence in Men

This study evaluated the relationship between serum testosterone levels and kidney stone prevalence in 6,633 male participants from the National Health and Nutrition Examination Survey 2011–2016. It found that lower quartiles of testosterone were associated with increased kidney stone risk, particularly in men aged 41–80. In the 41–60 age group, lower testosterone levels significantly increased the risk of kidney stones, while a non-linear relationship was observed in the 61–80 age group. No correlation was found in men aged 20–40. The study concluded that serum testosterone levels were inversely associated with kidney stone prevalence in men over 40, suggesting the need to redefine the role of testosterone in stone formation and further verify its effects.