TLDR Primary idiopathic pseudopelade of Brocq causes gradual, scarring hair loss with no effective treatment.
The document reported on five cases of primary idiopathic pseudopelade of Brocq (PPB), a rare and self-limiting hair disorder leading to progressive cicatricial alopecia. The patients, aged 29 to 45, exhibited asymptomatic, gradual hair loss with no inflammation or trauma history. Histopathology confirmed follicular scarring without other changes, supporting the diagnosis of primary idiopathic PPB. Despite treatment with intralesional triamcinolone acetonide, no significant response was observed. The study highlighted the lack of standard treatment for PPB and the need for further research into its pathogenesis and management.
42 citations,
January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
90 citations,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
49 citations,
April 2000 in “Journal of The American Academy of Dermatology” Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
80 citations,
March 2000 in “Journal of cutaneous pathology” The VVG stain effectively differentiates scar tissue from normal skin and helps classify types of permanent alopecia.
5 citations,
October 2018 in “Burns” Most patients who had scalp skin removed for burns as children had normal hair growth and were satisfied years later.
4 citations,
July 2015 in “Case Reports in Dermatology” A woman with unexplained hair loss was found to have harmless skin tumors and a scarring hair loss condition, but the tumors didn't cause the hair loss.