Potential Use of Human Periapical Cyst-Mesenchymal Stem Cells (hPCy-MSCs) as a Novel Stem Cell Source for Regenerative Medicine Applications

    Marco Tatullo, Bruna Codispoti, Andrea Pacifici, Francesca Palmieri, Massimo Marrelli, L Pacifici, Francesco Paduano
    TLDR Human periapical cyst stem cells could be a promising source for regenerative medicine.
    The document discussed the potential of human periapical cyst mesenchymal stem cells (hPCy-MSCs) as a novel source for regenerative medicine. These stem cells, derived from surgically removed periapical cysts, were highlighted for their regenerative capabilities, including differentiation into osteoblasts, adipocytes, and neurons. The ease of access and efficient isolation from oral tissues made hPCy-MSCs an attractive option for clinical applications. The review emphasized the potential of hPCy-MSCs to serve as a smart source of stem cells, utilizing biological waste without affecting healthy tissues, and suggested their promising role in future regenerative medicine.
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