Managing Hyperglycemia and Rash Associated With Alpelisib: Expert Consensus Recommendations Using the Delphi Technique

January 2024 in “ NPJ breast cancer ”

Emily J. Gallagher, Heather Moore, Mario E. Lacouture, Susan Dent, Azeez Farooki, Marcus D. Goncalves, Claudine Isaacs, Abigail Johnston, Dejan Juric, Zoe Quandt, Laura M. Spring, Brian Berman, Melanie Decker, Gabriel N. Hortobágyi, Benjamin H. Kaffenberger, Bernice Y. Kwong, Timothy Pluard, Ruta Rao, Lee S. Schwartzberg, Michael S. Broder

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Studysummary This study, using modified Delphi panels, provided consensus recommendations for managing alpelisib-induced hyperglycemia and rash, advising prophylactic metformin starting for certain risk groups and the use of nonsedating H1 antihistamines and topical steroids for initial rash management.

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