TLDR Topical minoxidil can rarely cause pleural effusion if ingested.
A rare case report describes a patient without chronic kidney disease who developed pleural effusion due to the unintentional oral consumption of topical minoxidil. The patient exhibited symptoms such as 90% oxygen saturation, dullness to percussion, asymmetrical chest expansion, and diminished air entry. Imaging revealed bilateral pleural opacities and minimal pleural effusions. Treatment with diuretics and airway management led to complete resolution. The report emphasizes that physicians should consider the rare side effects of topical minoxidil, including pleural effusion, in their differential diagnosis.
A woman's use of minoxidil for hair loss caused fluid buildup in her chest, which went away when she stopped using the product.
74 citations,
May 2004 in “Journal of Clinical Hypertension” Minoxidil effectively treats severe hypertension, but watch for side effects.
3 citations,
June 1997 in “Veterinary Dermatology” Minoxidil treatment can stimulate hair growth in hairless puppies if applied early.
16 citations,
May 1982 in “Postgraduate Medical Journal” Minoxidil can cause pericardial and pleural effusions with high protein content.
96 citations,
October 1981 in “Drugs” Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
49 citations,
January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil doesn't increase pericardial disorder risk, but may cause fluid accumulation.
August 2023 in “Journal of Cosmetic Dermatology” Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
14 citations,
January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
