Dietary Phytochemicals and Their Impact on Androgen Disorders in Males

May 2025 in “ IDOSR JOURNAL OF BIOLOGY CHEMISTRY AND PHARMACY ”

Nagawa Jackline Irene

dietary phytochemicals androgen disorders hypogonadism androgen deficiency androgenic alopecia flavonoids lignans polyphenols alkaloids androgen metabolism androgen receptor enzymatic modulation antioxidative properties anti-inflammatory properties hair loss male pattern baldness hormonal balance

TLDR Dietary phytochemicals may help improve male hormonal health.

The document reviews the potential impact of dietary phytochemicals on androgen disorders in males, such as hypogonadism, androgen deficiency, and androgenic alopecia. It discusses how these naturally occurring compounds, including flavonoids, lignans, polyphenols, and alkaloids, can influence androgen metabolism and receptor activity, thereby supporting hormonal balance. The phytochemicals exert their effects through enzymatic modulation, inhibition of androgen receptor signaling, and antioxidative and anti-inflammatory properties. The review suggests that understanding these mechanisms could lead to new therapeutic and dietary interventions to improve male hormonal health and calls for further research in this area.

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