Polycystic Ovary Syndrome: Role of Androgen Excess Self-Assessment in Diagnosis
January 2019
in “
OpenBU/Boston University Institutional Repository (Boston University)
”
Studysummary In this study, women with a PCOS diagnosis were more likely to report clinical signs of androgen excess, including hirsutism, acne, and alopecia, with ethnic patterns in symptom prevalence.
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The study on polycystic ovary syndrome (PCOS) conducted at Boston University School of Medicine involved 249 women aged 18-45 and highlighted ethnic variations in the clinical signs of androgen excess, such as hirsutism, acne, and alopecia. The results showed that 22.5% of participants had clinical hirsutism, with the highest mean scores in South Asian and Hispanic women. Moderate-severe acne was reported by 23.6% of respondents, with the highest prevalence in South Asian women. Alopecia was reported by 9.4% of participants, most commonly among Black and East Asian women. Women with a PCOS diagnosis were more likely to exhibit these signs compared to those without a diagnosis. Additionally, 33% of women who consented to medical record validation had elevated testosterone levels. The study concluded that there was an ethnic-dependent pattern in the development of androgen excess symptoms, and these symptoms were more prevalent in women diagnosed with PCOS.