PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities?

    December 2021 in “ International Journal of Biomedicine ”
    A. V. Atalyan, Eldar Sharifulin, Л. В. Лазарева, Yana Nadelyaeva, L. V. Suturina
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    TLDR Hyperprolactinemia should be treated before confirming a PCOS diagnosis.
    The document discusses the complex relationship between hyperprolactinemia and PCOS, noting that although hyperprolactinemia is typically excluded in PCOS diagnosis, it has been found in some PCOS patients. The authors propose the term "potential PCOS" for cases with hyperprolactinemia until it is treated and symptoms are re-evaluated. They call for more research to understand the link between these conditions, including studies on asymptomatic hyperprolactinemia and macroprolactin. The review concludes that a definitive PCOS diagnosis should be made only after hyperprolactinemia is addressed and symptoms are reassessed.
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