Papilledema and Hypervitaminosis A

    August 1970 in “ JAMA
    G Morrice
    TLDR Excessive vitamin A can cause symptoms that mimic serious brain conditions.
    The document discussed cases of papilledema associated with hypervitaminosis A, particularly in young females. It referenced a case of an 18-year-old girl with pseudotumor cerebri linked to excessive vitamin A intake, observed at Ohio State University Hospital. Additionally, it mentioned a 1958 case of a 14-year-old girl with symptoms including bilateral papilledema, hair loss, skin changes, and other systemic issues, confirmed to be due to hypervitaminosis A. Further cases from 1960 involved three girls aged 14 to 16, who exhibited symptoms like diplopia and papilledema, alongside alopecia and skin conditions, all suggesting a misdiagnosis of brain tumors. These cases highlighted the potential for hypervitaminosis A to mimic serious neurological conditions.
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