Papilledema and Hypervitaminosis A

    August 1970 in “ JAMA ”
    G Morrice
    TLDR Excessive vitamin A can cause symptoms that mimic serious brain conditions.
    The document discussed cases of papilledema associated with hypervitaminosis A, particularly in young females. An 18-year-old girl developed pseudotumor cerebri due to excessive vitamin A intake, as reported by Fedontin. Historical cases included a 14-year-old girl with symptoms such as bilateral papilledema, hair loss, skin changes, and other systemic issues, confirming hypervitaminosis A through serum vitamin A levels. Morrice et al. described three additional cases in teenage girls presenting with symptoms like diplopia and papilledema, alongside alopecia and skin conditions. These cases highlighted the link between excessive vitamin A and neurological as well as dermatological symptoms.
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