Duration of Minoxidil Therapy to Yield Maximum Benefit

    October 1988 in “ Archives of Dermatology
    Robert L. Rietschel
    TLDR Minoxidil's benefits may decrease after two years of use.
    The study investigated the duration of minoxidil therapy needed to achieve maximum benefit in hair growth. It noted a decrease in total hair counts between the 12th and 30th month of use, particularly in subjects with average and above-average responses. The study began with 149 subjects, with 102 completing 12 months and 89 completing two years. Only 54 participants (50 men and 4 women) continued into the third year. The findings suggested that while minoxidil was effective, its benefits might diminish over time, highlighting the importance of long-term follow-up to determine the optimal duration of therapy.
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