Duration of Minoxidil Therapy to Yield Maximum Benefit

October 1988 in “ Archives of Dermatology ”

Robert L. Rietschel

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TLDR Minoxidil's benefits may decrease after two years of use.

The study observed the effects of minoxidil on hair growth over an extended period, noting a decrease in total hair counts between the 12th and 30th month of use, even among those with average and above-average responses. Initially, 149 subjects participated, but only 102 completed 12 months, and 89 completed two years. By the third year, only 54 subjects (50 men and 4 women) continued. The findings suggested that while minoxidil showed efficacy in promoting terminal hair growth, the benefits might diminish over time, highlighting the need for long-term studies to determine the optimal duration of therapy for maximum benefit.

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community Why don't Minoxidil regenerated hairs become terminal on the head?

in Minoxidil 101 upvotes 11 months ago

Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.

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At this point. In this conversation, users discussed the risks of drinking topical minoxidil and suggested alternative treatments such as obtaining a prescription for oral minoxidil or finasteride.

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in Minoxidil 141 upvotes 8 months ago

Oral minoxidil can increase body hair growth, but effects differ among individuals. Some recommend topical minoxidil to prevent unwanted body hair while preserving scalp hair.

community Why do Minoxidil gains need continued Minoxidil to be kept and can´t be retained with DHT blockers?

in Chat 66 upvotes 3 months ago

Minoxidil and finasteride work through different mechanisms; minoxidil-dependent hair requires continued use to maintain growth, while finasteride prevents further hair loss but cannot sustain minoxidil gains alone. Current treatments like minoxidil, finasteride, and others need indefinite use, as no permanent solution exists yet.

community Meta analysis of minoxidil only vs 5AR inhibitors

in Research/Science 58 upvotes 10 months ago

Oral dutasteride is the most effective for hair regrowth, followed by oral finasteride and minoxidil. Topical finasteride combined with minoxidil is recommended for those avoiding systemic DHT reduction.

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PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

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research Duration of Minoxidil Therapy to Yield Maximum Benefit

1 citations , October 1988 in “Archives of Dermatology”

Minoxidil's hair growth benefits may decrease over time.