Obesity and Low-Grade Inflammation among Young Finnish Men with Early-Onset Alopecia

The study investigated the association between early-onset alopecia and low-grade inflammation in young Finnish men, using high-sensitivity C-reactive protein (hs-CRP) as a marker. The study included 727 men aged 25-34 years. Results indicated that men with moderate to extensive alopecia had higher body mass index and larger body measurements compared to those with little to no alopecia. Although differences in waist-to-hip ratio, diastolic blood pressure, and hs-CRP were not statistically significant, an increase in hs-CRP was associated with an increase in waist-to-hip ratio among men with more severe alopecia. The findings suggested a link between moderate to extensive alopecia and low-grade inflammation, which is a predictor of future cardiovascular disease, particularly when combined with central obesity in men under 35 years.