NFAT5 Mediates Hypertonic Stress-Induced Atherosclerosis via Activating NLRP3 Inflammasome in Endothelium

    August 2019 in “ Cell Communication and Signaling ”
    Pingping Ma, Shenfang Zha, Xinkun Shen … Wanqian Liu
    Studysummary This study identifies NFAT5 as a crucial transcription factor necessary for triggering innate immune responses in the blood vessel lining that lead to atherosclerosis under hypertonic stress conditions.
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