Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6

January 2025 in “ Proceedings of the National Academy of Sciences ”

Yaning Duan, Zhenmei Xu, Boyu Hao, Anqi Zhang, Changyou Guo, Yuanzheng He

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Research cited in this study

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research Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, P2Y5/LPA6

253 citations , April 2009 in “Journal of Biological Chemistry”

p2y5, now called LPA6, is a receptor important for human hair growth.

research Disruption of P2RY5, an Orphan G Protein–Coupled Receptor, Underlies Autosomal Recessive Woolly Hair

210 citations , February 2008 in “Nature genetics”

Mutations in the P2RY5 gene cause autosomal recessive woolly hair.