Influence of Climate Factors on Pediatric Alopecia Areata Flares in Philadelphia, Pennsylvania

    October 2021 in “ Scientific Reports ”
    Elisabeth A. George, Leslie Castelo‐Soccio, Elana Putterman, Helena Kuhn, Carlos Gustavo Wambier, Abrar A. Qureshi, Eunyoung Cho
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    Studysummary This study suggests that certain climate factors, particularly UV index and precipitation, may influence seasonal flare patterns in children with alopecia areata, especially those with atopic conditions.
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    This study investigated the influence of climate factors on alopecia areata (AA) flares in 336 children in Philadelphia from 2015 to 2017. Significant correlations were found between AA flare frequency and climate variables such as UV index, precipitation, number of days with rain, number of days with sun, and air pressure. The study revealed that patients with atopic comorbidities showed stronger associations with these climate factors, suggesting they might be more susceptible to climate influences on AA flares. In contrast, patients without atopic comorbidities exhibited weaker and non-significant correlations. The findings indicated that climate factors could mediate the seasonal pattern of AA flares and contribute to AA pathogenesis.
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