Minoxidil and Tail-Like Effect in Alopecia Areata

    September 1987 in “ International Journal of Dermatology
    Jim Baral
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    TLDR Minoxidil caused hair to grow in unintended areas, like a tail, in a young girl.
    In 1987, Dr. Jim Baral reported on the case of a 2½-year-old girl with alopecia areata who experienced hair regrowth in unintended areas after using 3% minoxidil. The girl initially presented with three to seven lesions on her scalp and received intralesional injections of 2.5% triamcinolone acetonide, along with topical applications of betamethasone dipropionate ointment and 3% minoxidil twice daily. Hair regrowth was first noted on June 5, 1986, and by August 21, 1986, significant hair growth was observed on her forehead, nape of the neck, and sacroiliac area, with the latter showing a tail-like effect. Dr. Baral also mentioned previous cases where patients, including 27-year-old female twins and a male patient, experienced remote hair growth after using topical minoxidil. The document also includes a brief mention of a separate correspondence regarding the treatment of female androgenetic alopecia with cimetidine, but this is not the focus of the summary.
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