Microscopic Polyangiitis Secondary to Mycobacterium Abscessus in a Patient with Bronchiectasis: A Case Report
November 2018
in “
BMC Pulmonary Medicine
”
Studysummary This case report describes the first instance of ANCA positive vasculitis secondary to Mycobacterium abscessus pulmonary disease, highlighting the complex interplay of immune dysfunction and treatment challenges.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document reported a case of a 70-year-old female with bronchiectasis who developed microscopic polyangiitis (MPA) secondary to Mycobacterium abscessus infection. The patient faced significant complications, including small joint arthralgia, sensorimotor neuropathy, and retinal vein occlusion, and experienced drug intolerances and adverse effects such as alopecia and Achilles tendonitis. Treatment involved a complex regimen of immunosuppressive and antimicrobial therapies, highlighting the difficulty of balancing these treatments. The case emphasized the importance of investigating immune function in patients with mycobacterial infections and was the first to document ANCA-positive vasculitis secondary to M. abscessus, underscoring the intricate relationship between mycobacterial infection and immune dysfunction.
