Microscopic Polyangiitis Secondary to Mycobacterium Abscessus in a Patient with Bronchiectasis: A Case Report

    November 2018 in “ BMC Pulmonary Medicine
    C. Addy, GR Doran, A. Jones, Gary Wright, S. Caskey, D.G. Downey
    TLDR A 70-year-old woman with bronchiectasis developed a rare immune disease due to a bacterial infection, requiring a difficult balance of treatments.
    The document reported a case of a 70-year-old female with bronchiectasis who developed microscopic polyangiitis (MPA) secondary to Mycobacterium abscessus infection. The patient faced significant complications, including small joint arthralgia, sensorimotor neuropathy, and retinal vein occlusion, and experienced drug intolerances and adverse effects such as alopecia and Achilles tendonitis. Treatment involved a complex regimen of immunosuppressive and antimicrobial therapies, highlighting the difficulty of balancing these treatments. The case emphasized the importance of investigating immune function in patients with mycobacterial infections and was the first to document ANCA-positive vasculitis secondary to M. abscessus, underscoring the intricate relationship between mycobacterial infection and immune dysfunction.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 110 results

      community How true is the statement: dead follicles don't grow back?

      in Research/Science  107 upvotes 4 weeks ago
      Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.

      community Oral minoxidil and oral finasteride progress

      in Progress Pictures  58 upvotes 2 months ago
      The user has been using oral finasteride 1mg and oral minoxidil 2.5mg daily since late 2024 and reports positive progress in hair growth without side effects, though some unwanted hair growth on hands and arms. The user is 26 years old and started losing hair around age 20 or 21.

      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  261 upvotes 4 months ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

    Similar Research

    5 / 1000+ results
      Index

      research Index

      November 2019 in “Harper's Textbook of Pediatric Dermatology”
      The document is a detailed medical reference on skin and genetic disorders.
      Proceedings of the RAMI Intern Section Meeting, 18th January 2014

      research Proceedings of the RAMI Intern Section Meeting, 18th January 2014

      2 citations, July 2014 in “Irish Journal of Medical Science”
      The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.
      Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

      research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

      47 citations, December 2019 in “Frontiers in immunology”
      A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
      Subject Index

      research Subject Index

      March 2014 in “Journal of The American Academy of Dermatology”
      The document lists various dermatology topics, treatments, and diagnostic methods.