Microscopic Polyangiitis Secondary to Mycobacterium Abscessus in a Patient with Bronchiectasis: A Case Report

    November 2018 in “ BMC Pulmonary Medicine ”
    C. Addy, GR Doran, A. Jones, Gary Wright, S. Caskey, D.G. Downey
    TLDR A 70-year-old woman with bronchiectasis developed a rare immune disease due to a bacterial infection, requiring a difficult balance of treatments.
    The document reported a case of a 70-year-old female with bronchiectasis who developed microscopic polyangiitis (MPA) secondary to Mycobacterium abscessus infection. The patient faced significant complications, including small joint arthralgia, sensorimotor neuropathy, and retinal vein occlusion, and experienced drug intolerances and adverse effects such as alopecia and Achilles tendonitis. Treatment involved a complex regimen of immunosuppressive and antimicrobial therapies, highlighting the difficulty of balancing these treatments. The case emphasized the importance of investigating immune function in patients with mycobacterial infections and was the first to document ANCA-positive vasculitis secondary to M. abscessus, underscoring the intricate relationship between mycobacterial infection and immune dysfunction.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 152 results

      community Hair disappearing after one week (microscope photos)

      in Progress Pictures  752 upvotes 3 months ago
      A user is concerned about hair loss despite using finasteride and minoxidil, noting changes in hair under a microscope after one week. Others suggest patience, as hair treatments take months to show results, and recommend focusing less on microscopic changes.

      community VT Reedle Shot for hair growth?

      in Microneedling  1 upvotes 2 weeks ago
      The VT Reedle Shot, a skincare product using silica spicules, is discussed as a potential at-home alternative to microneedling for hair regrowth. It is suggested that different intensities may aid in hairline regrowth.

      community Two months min+fin+dermaroll results

      in Is this regrowth?  16 upvotes 4 months ago
      The conversation is about hair regrowth results after two months using oral finasteride, oral and topical minoxidil, and weekly dermarolling. The user shared before and after photos to show progress.

      community How true is the statement: dead follicles don't grow back?

      in Research/Science  107 upvotes 8 months ago
      Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.

    Similar Research

    5 / 1000+ results
      Index

      research Index

      November 2019 in “Harper's Textbook of Pediatric Dermatology”
      The document is a detailed medical reference on skin and genetic disorders.
      Proceedings of the RAMI Intern Section Meeting, 18th January 2014

      research Proceedings of the RAMI Intern Section Meeting, 18th January 2014

      2 citations , July 2014 in “Irish Journal of Medical Science”
      The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.
      Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

      research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

      47 citations , December 2019 in “Frontiers in immunology”
      A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
      Subject Index

      research Subject Index

      March 2014 in “Journal of The American Academy of Dermatology”
      The document lists various dermatology topics, treatments, and diagnostic methods.