Microneedling with topical administration of bleomycin as a treatment method for plantar warts

The study explored the use of microneedling combined with topical administration of bleomycin as a treatment for plantar warts, which are caused by various HPV viruses. Bleomycin's efficacy in treating plantar warts varied widely from 16% to 97% depending on its concentration and administration method. Microneedling was found to enhance the effectiveness of bleomycin by improving its penetration, leading to faster response times and fewer treatment sessions. The relapse rate with this method was comparable to other injection-based treatments.