The Expression Characteristics and Their Biological Significance of Epidermal Growth Factor and Basic Fibroblast Growth Factor in Rat Skins at Different Development Stages
January 2001
in “
Chinese Journal of Reparative and Reconstructive Surgery
”
New to Epidermal Growth Factor? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that endogenous EGF may play a role in epidermal development and wound healing, while the absence of bFGF in embryonic rats' skin could contribute to non-scar healing.
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The study investigated the expression of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) in rat skin across different developmental stages. EGF was present in the skin of embryonic, newborn, and adult rats, with increasing expression as the rats aged, suggesting its role in epidermal development and wound healing. In contrast, bFGF was absent in embryonic skin but present in newborn and adult rats, indicating that the lack of bFGF might contribute to non-scar healing during the embryonic stage.
