Report: Metformin Potential in Predisposing Arthralgia, Type II Cross Reactivity Secondary to Group A Streptococcus Infection and Other Comorbidities in Treating PCOS
May 2019
in “
PubMed
”
New to Metformin? There is a guide in the encyclopedia. Read the guide → Studysummary This report presents a case of a female with PCOS treated with metformin who developed hyperuricemia, severe joint and neurological pain, and later experienced a hypersensitivity reaction to benzathine benzyl penicillin.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document reported on a case of a female with Polycystic Ovarian Syndrome (PCOS) treated with metformin for over two years, who subsequently developed hyperuricemia, migraine, neurological pain, severe joint and knee pains, and rheumatic fever. Treatment with benzathine benzyl penicillin for rheumatic fever led to a Type IV delayed hypersensitivity reaction. The report highlighted the potential adverse effects of metformin, including back pain, swollen joints, and rare behavioral alterations, and discussed the risks of allergic reactions to penicillin, which affects 10% of patients.
