The Expression of Melatonin Receptor in Human Hypertrophic Scar

May 2010 in “ Chinese journal of plastic surgery ”

Juncheng Zhang, Yuan Xie, Si-juan Liu, Libing Dai, Jianping Li

melatonin melatonin receptor hypertrophic scar scar formation therapeutic interventions

TLDR Melatonin might help treat thick scars.

The study investigated the expression of melatonin receptors in human hypertrophic scar tissue. The research aimed to understand the role of melatonin in the formation and development of hypertrophic scars. The findings suggested that melatonin receptors were present in hypertrophic scar tissues, indicating that melatonin might play a role in scar formation and could potentially be targeted for therapeutic interventions in the future.

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community Melatonin a possible tool to help fight AGA hair loss.

in Research/Science 50 upvotes 3 years ago

Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

community Have you guys heard about topical melatonin?

in Research 11 upvotes 4 years ago

Topical melatonin may improve hair density and thickness, and reduce hair loss and seborrhea with no significant side effects. The user made their own melatonin solution for hair treatment.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Optimal dose for topical Melatonin

in Treatment 6 upvotes 1 year ago

The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

community Does melatonin dissolve in isopropyl alcohol

in Technology 7 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

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research Metallothionein Expression During Wool Follicle Development in Fetal Sheep

January 1999 in “Birkhäuser Basel eBooks”

Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.