Matrix-Degrading Type II Transmembrane Serine Protease Matriptase: Its Role in Cancer Development and Malignancy

October 2006

Ming‐Shyue Lee

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4 / 4 results

research Delineation of Matriptase Protein Expression by Enzymatic Gene Trapping Suggests Diverging Roles in Barrier Function, Hair Formation, and Squamous Cell Carcinogenesis

100 citations , May 2006 in “American Journal Of Pathology”

Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.

Matriptase Activation and Shedding with HAI-1 Induced by Steroid Sex Hormones in Human Prostate Cancer Cells, but Not in Breast Cancer Cells

research Matriptase Activation and Shedding with HAI-1 Induced by Steroid Sex Hormones in Human Prostate Cancer Cells, but Not in Breast Cancer Cells

56 citations , February 2006 in “American journal of physiology. Cell physiology”

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

research Matriptase: Potent Proteolysis on the Cell Surface

165 citations , January 2006 in “Molecular Medicine”

Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.

research Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis

324 citations , May 2002 in “Oncogene”