Massive Pulmonary Embolism: Evolving Management and Future Therapies

    November 1963 in “ JAMA
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    TLDR Timely diagnosis and active treatment improve outcomes for massive pulmonary embolism.
    The document discusses the evolving management of massive pulmonary embolism, highlighting the transition from purely prophylactic measures to more active therapies, including cardiopulmonary bypass and potential future use of thrombolytic enzyme therapy. It emphasizes the importance of timely diagnosis and treatment to improve patient outcomes. Additionally, it reviews a study on alopecia areata involving 736 cases over 10 years at the Mayo Clinic, noting the condition's tendency to recur, its association with emotional stress, and the importance of realistic patient counseling.
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