Managing Skin Diseases That Flare During Pregnancy and in the Postpartum Period: Part 2 - Management and Safety Considerations
February 2026
in “
Journal of the American Academy of Dermatology
”
TLDR Managing skin diseases during pregnancy and postpartum requires careful consideration of treatment safety and dosing to protect both mother and baby.
The document discusses the challenges and considerations in managing skin diseases that flare during pregnancy and the postpartum period. It highlights the fragmented nature of therapeutic options and the lack of comprehensive safety and dosing data for treatments such as biologics, immunomodulators, and phototherapy. The exclusion of pregnant and lactating women from clinical trials leaves significant gaps in understanding the pharmacokinetics and teratogenic risks of these treatments. The paper provides an evidence-based framework for managing conditions like atopic dermatitis, psoriasis, acne, rosacea, melasma, alopecia, and hidradenitis suppurativa, emphasizing the importance of safety profiles, trimester-specific dosing, and lactation pharmacology to optimize maternal health while minimizing risks to the fetus and neonate.
