Interactions Between Malassezia Restricta and the Human Mycobiome: A Comprehensive Perspective

    August 2024 in “ Revista Científica Multidisciplinar Núcleo do Conhecimento ”
    Maria Vitória Cavalheiro Berlofa, Ana Carolina de Oliveira Ramos Siqueira, Yara Natércia Lima Faustino de Maria, Rafaela de Campos Oliveira, Paulo Salarrola Takao, Autitony Camurça da Silva, Milena Coutinho Natucci, Fabiano Bezerra Menegídio, Daniela Jabés
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    Studysummary This source reports that Malassezia restricta appears more abundantly in fecal samples and may be associated with intestinal diseases such as Crohn's disease and ulcerative colitis, but is also found in healthy contexts; future research could inform targeted therapies. Our plain-language summary of this paper — not a Tressless recommendation.
    Malassezia restricta, a prevalent fungus in the human skin microbiota, has been identified in various anatomical niches, both healthy and dysbiotic, through advanced sequencing methods. A review of 14 studies highlights its presence in oral, intestinal, and respiratory areas, with a notable association with inflammatory bowel diseases like Crohn's disease and ulcerative colitis. These findings suggest that Malassezia restricta may play a role in intestinal diseases, as it is abundant in fecal samples from both healthy and pathological contexts. Future research could enhance understanding of its role in intestinal dysbiosis and lead to new therapeutic approaches.
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