Interactions Between Malassezia Restricta and the Human Mycobiome: A Comprehensive Perspective

Malassezia restricta, a prevalent fungus in the human skin microbiota, has been identified in various anatomical niches, both healthy and dysbiotic, through advanced sequencing methods. A review of 14 studies highlights its presence in oral, intestinal, and respiratory areas, with a notable association with inflammatory bowel diseases like Crohn's disease and ulcerative colitis. These findings suggest that Malassezia restricta may play a role in intestinal diseases, as it is abundant in fecal samples from both healthy and pathological contexts. Future research could enhance understanding of its role in intestinal dysbiosis and lead to new therapeutic approaches.