<p>Study of the interaction between self-assembling peptide and mangiferin and in vitro release of mangiferin from in situ hydrogel</p>

    September 2019 in “ International Journal of Nanomedicine ”
    Meng Cui, Weipeng Wei, Yuhe Wang, Kunqin Zhang, Ting Zhang, Yunyan Tang, Fushan Tang
    TLDR RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.
    The study explored the interaction between the self-assembling peptide RADA16-I and mangiferin (MA), focusing on the potential of RADA16-I as a delivery system for the hydrophobic drug MA. The research demonstrated that RADA16-I could effectively encapsulate and release MA in vitro, suggesting its promise as a delivery vehicle for hydrophobic drugs. This finding indicated that RADA16-I might enhance the solubility and bioavailability of such drugs, providing a novel approach for drug delivery systems.
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