Low-Dose Oral Minoxidil in Frontal Fibrosing Alopecia: Series of 122 Patients

    November 2024 in “ Actas Dermo-Sifiliográficas ”
    Cristina Pindado‐­Ortega, Rodrigo Pirmez, DanielFernandes Melo, L Junqueira Fortes Binato, M.L. Porriño-Bustamante, J Barreto Carpi, R. Gil-Redondo, Ángela Hermosa‐Gelbard, Juan ­Jimenez‐Cauhe, David Saceda‐Corralo, Sérgio Vañó-Galván
    The study evaluated the effectiveness of low-dose oral minoxidil in treating frontal fibrosing alopecia (FFA) in 122 patients across centers in Brazil and Spain. Results showed that 45.1% of patients experienced subjective improvement in the frontotemporal hairline, with varying degrees of mild (34.4%), moderate (9.0%), and excellent (1.6%) improvement. Additionally, 57.4% saw improved hair density in the interparietal area, while 25.4% and 3.3% experienced eyebrow and eyelash growth, respectively. Adverse effects were reported in 33.6% of patients, with hypertrichosis being the most common at 23.8%. The study concluded that oral minoxidil is an effective additional therapy for FFA, enhancing hair and eyebrow growth and frontotemporal hairline density.
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