Late Unexpected Consequences of COVID-19 Infection in Survivors of Acute Hypoxic Respiratory Failure

    August 2021 in “ Internal Medicine Journal
    Lucrezia De Michele, Paola Pierucci, Giovanna Elisiana Carpagnano, Domenico Bonamonte, Francesca Ambrogio, Guido Giovannetti, Michela Dimitri, Carlo D'Agostino
    Image of study
    TLDR After severe COVID-19, 71% of patients experienced excessive hair shedding and thinning within 3 months due to factors like low oxygen levels, medication, stress, and autoimmune disease.
    A prospective single-centre study conducted from May to July 2020 involving 38 COVID-19 survivors of severe hypoxic respiratory failure found that 71% of these patients developed telogen effluvium (TE) alopecia within 3 months after discharge. TE is a scalp disorder characterized by excessive shedding and thinning of hair, often related to drugs, trauma, and emotional and physiological stress. The study suggests that the onset of TE in these patients could be attributed to several factors: severe prolonged hypoxia, increased androgen receptor related pathway, drugs used during admission, stress, and autoimmune disease. The severe hypoxia experienced by these patients could have led to a lower or insufficient blood supply to the scalp tissues, contributing to TE alopecia. Further studies are needed to better understand these hypothesized mechanisms or potential correlations among them.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 404 results

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community A Different Take on Curing MBP

       16 upvotes 5 years ago
      Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Is this broscience? From More Plates, More Dates

      in Research/Science  22 upvotes 8 months ago
      The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

    Related Research

    6 / 6 results