TLDR Keratinocytes help manage skin nitrogen metabolism, varying by age and skin area.
The study investigated the role of keratinocytes as a storage site for ammonium-inducible glutamine synthetase in human and rat skin, focusing on how its distribution varied with age and anatomical location. The research found that the presence of glutamine synthetase in keratinocytes was influenced by both the age of the individual and the specific area of the skin. This suggested that keratinocytes played a significant role in managing nitrogen metabolism in the skin, with potential implications for understanding skin physiology and pathology.
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