Iododerma in pregnancy secondary to iodinated multivitamins

The document reports a case of allergic contact dermatitis in a 61-year-old man who used topical brimonidine for facial erythema associated with rosacea. Despite a history of various treatments, he developed a burning sensation, swelling, and erythema with scaling and mild crusting on his face after using brimonidine. A clinical diagnosis of allergic contact dermatitis was made, and he was treated with prednisolone, cephalexin, and hydrocortisone ointment, while discontinuing minocycline and brimonidine. Patch testing confirmed a positive reaction to brimonidine, among other substances. The document highlights the potential for allergic contact dermatitis from brimonidine, noting that adverse event reports from clinical trials indicate its occurrence in 1% of subjects, while ocular allergy to brimonidine has been described as ranging from 14 to 26%. The patient was able to continue oral clonidine for flushing without an allergic reaction. The authors emphasize the importance of recognizing the potential for allergic contact dermatitis with the increased availability of brimonidine.