Pioneers in Dermatology and Venereology: An Interview with Professor Rudolf Happle

The interview with Professor Rudolf Happle highlights his distinguished career in dermatology, focusing on his contributions to genodermatology and hair diseases, particularly alopecia areata. Despite initial aspirations in surgery, Happle found his calling in dermatological science, influenced by his experiences in Freiburg and collaborations with colleagues like Karin Echternacht. Together, they developed treatments for alopecia areata using contact allergens, although challenges in conducting blinded studies were noted. Happle emphasizes the importance of rationalism in science, inspired by philosopher Karl R. Popper, and expresses concerns about the commercialization of dermatology. He advises aspiring dermatologists to engage in research centers for scientific careers and cautions against the pitfalls of academic publishing. His work on mosaicism in human skin is also noted, with a second edition of his book published in 2023.