Index of the Human Papillomavirus (HPV) Vaccine Industry Clinical Study Programs and Non-Industry Funded Studies: A Necessary Basis to Address Reporting Bias in a Systematic Review

The document discussed efforts to create a comprehensive index of HPV vaccine study programs, noting that only one of four manufacturers contributed information, and 20% of the index lacked cross-verification. Despite these challenges, the indexed study programs were more extensive than those used by major regulators like the EMA and FDA, which based approvals on only half of the available trials. The authors advocated for the registration and publication of all studies and data to minimize reporting bias in systematic reviews.