Contribution Of In-Utero Drug Exposure When Interpreting Hair Results In Young Children

    Pascal Kintz
    TLDR Hair analysis alone can't confirm long-term drug exposure in children under 1 year old.
    The study examined drug concentrations in the hair of two children whose mothers admitted to drug use during pregnancy. In case 1, THC levels were 0.42, 0.51, and 0.86 ng/mg in different hair segments, with cannabinol and cannabidiol also present. In case 2, methadone levels were 0.42, 0.46, 0.59, and 1.58 ng/mg, with EDDP detected in the last two segments. The low concentrations suggested infrequent exposure, and the parents denied postnatal drug administration. Four possible interpretations were proposed: decreased recent administration, increased body weight diluting concentrations, sweat contamination, and in-utero exposure. The study highlighted the lack of data on drug disappearance from hair post-pregnancy.
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